
Haystack MRD® by Quest Diagnostics®
Haystack MRD by Quest Diagnostics sells a cancer test that detects residual disease after treatment by analyzing circulating tumor DNA. The company has 60 employees and raised $56M in a Series A round in November 2022.
The growth story

Haystack MRD® by Quest Diagnostics® grew from 5 to 60 employees between 2021 and 2026, raising $56M along the way, most recently a Series A in November 2022.
About
Haystack MRD provides a tumor-informed test that uses next-generation sequencing to identify minimal residual disease in cancer patients. The test is designed to help clinicians make treatment decisions by detecting ultralow levels of circulating tumor DNA, leveraging over 20 years of clinical development and technology from Johns Hopkins University.
The company, founded in 2021, has grown to 60 employees and secured $56M in Series A funding in late 2022. Its investors include Alexandria Venture Investments, Bruker, Catalio Capital Management, and Exact Ventures.
Founders and leadership
Haystack MRD's largest function is sales, with 14 employees dedicated to this area. The company is headquartered in Baltimore, Maryland, and has a median employee tenure of 2 years.











The Haystack MRD® by Quest Diagnostics® org chart
Dan Edelstein (Chief Executive Officer) leads 21 mapped leaders with 11 direct reports. Click +N to expand a team; names link to the person’s public profile.
Departments, and which ones grew

Headcount by function: Research 21 (-9% YoY), Sales 14 (+27% YoY), Quality Assurance 5 (+25% YoY), Information Technology 3 (+50% YoY), Engineering 3 (0% YoY), Operations 3 (+50% YoY).
Talent flow
The company recruits heavily from Sysmex Inostics, Guardant Health, and Myriad Genetics, with 10, 6, and 5 hires respectively. Alumni often move to Quest Diagnostics, BillionToOne, and Natera.

Most common previous employers of Haystack MRD® by Quest Diagnostics® staff: Sysmex Inostics (10), Guardant Health (6), Myriad Genetics (5), Natera (3), Inostics (2), Aspira Women's Health (2). Former Haystack MRD® by Quest Diagnostics® employees most often moved to Quest Diagnostics (3), BillionToOne (2), Natera (2), Myriad Genetics (2), Avant Genomics (2), Catalio Capital Management (1).
Alumni worth knowing








Web traffic

Traffic mix: 76% direct, 4% search, 4% social, 0% paid.
What this company is made of

Most common skills at Haystack MRD® by Quest Diagnostics®: Microsoft Office (21), Polymerase Chain Reaction (PCR) (19), Leadership (19), Data Analysis (17), Molecular Biology (16), Sales (15), Microsoft Excel (15), Cell Culture (15).
Where the team actually sits

Haystack MRD® by Quest Diagnostics® people are concentrated in Maryland, United States (8), Greater Hamburg Area (4), Hamburg, Germany (3), Greater Philadelphia (2).
Search footprint
Haystack MRD® by Quest Diagnostics® attracts about 41 organic search visits a month, traffic worth roughly $0K a month if bought through ads. It gained 64 ranking keywords and lost 13 in the last period.
Frequently asked
Haystack MRD® by Quest Diagnostics® has 60 employees as of September 2026.
Haystack MRD® by Quest Diagnostics® has raised $56M in total, most recently a Series A round in November 2022.
Dan Edelstein (Chief Executive Officer) sits at the top of Haystack MRD® by Quest Diagnostics®'s reporting structure, with 11 direct reports.
The most common previous employers of current Haystack MRD® by Quest Diagnostics® staff are Sysmex Inostics (10 people), Guardant Health (6 people), Myriad Genetics (5 people).
Former Haystack MRD® by Quest Diagnostics® employees most often move to Quest Diagnostics (3), BillionToOne (2), Natera (2).
Haystack MRD® by Quest Diagnostics® attracts about 41 organic search visits a month, worth roughly $0K a month in equivalent ad spend.
The most common skills among Haystack MRD® by Quest Diagnostics® staff are Microsoft Office, Polymerase Chain Reaction (PCR), Leadership, Data Analysis, Molecular Biology.
Haystack MRD® by Quest Diagnostics® staff are concentrated in Maryland, United States (8), Greater Hamburg Area (4), Hamburg, Germany (3).
Haystack MRD® by Quest Diagnostics® has about 21 people in Research, down 9% over the past year, as of September 2026.
Haystack MRD® by Quest Diagnostics® has about 14 people in Sales, up 27% over the past year, as of September 2026.
Computed from 45 current and 32 former Haystack MRD® by Quest Diagnostics® profiles, as of September 2026. Source: Crustdata.
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