Orionis Biosciences

Biotechnology ResearchWaltham, Massachusetts, United StatesFounded 201567 employees$79M raised

Orionis Biosciences is a biotechnology company developing novel immunotherapies for cancer treatment using proprietary drug discovery platforms. The company has raised $79 million, including a Series C in 2022 with backing from Novartis and other healthcare investors.

Employees
67
Total raised
$79M
Last: Series C
Site visitors
4K
per month
Alumni founders

The growth story

Orionis Biosciences headcount and funding67 people today
67$55M6720222023202420252026
Data by CrustdataCrustdata

Orionis Biosciences grew from 38 to 67 employees between 2022 and 2026, raising $79M along the way, most recently a Series C in October 2022.

About

Orionis Biosciences develops biologics and small molecule therapies through its A-Kine and Allo-Glue platforms, which aim to reprogram disease states. Its pipeline focuses on cancer immunotherapies.

The company has 67 employees and maintains strong ties to Belgian research institutions, with many team members coming from Ghent University and VIB. Its $79 million funding includes participation from strategic investor Novartis.

Founders and leadership

Research dominates Orionis' organization, with 29 employees in that function. The company shows stability with a median tenure of 5 years among its 67-person team.

The Orionis Biosciences org chart

Nikolai Kley (Founder, President and CEO) leads 16 mapped leaders with 7 direct reports. Click +N to expand a team; names link to the person’s public profile.

Departments, and which ones grew

Headcount by functiongrowth vs 12 months ago
RResearch
43+16%
BBusiness Development
8+60%
EEngineering
4+33%
PProgram and Project Management
3+200%
Data by CrustdataCrustdata

Headcount by function: Research 43 (+16% YoY), Business Development 8 (+60% YoY), Engineering 4 (+33% YoY), Program and Project Management 3 (+200% YoY).

Talent flow

Orionis recruits heavily from Ghent University (12 alumni) and VIB (7), with additional hires from cancer research centers like Dana-Farber. Alumni have moved to biotechs including argenx and Legend Biotech.

Where Orionis Biosciences people come from, and where they go53 current + 22 former profiles
10 people: Ghent University → Orionis Biosciences7 people: VIB → Orionis Biosciences6 people: Forma Therapeutics (Now Novo Nordisk) → Orionis Biosciences3 people: Dana-Farber Cancer Institute → Orionis Biosciences3 people: KU Leuven → Orionis Biosciences3 people: VIB-UGent → Orionis Biosciences2 people: Mass General Brigham → Orionis Biosciences2 people: Merck → Orionis Biosciences2 people: Orionis Biosciences → argenx1 people: Orionis Biosciences → Kata1 people: Orionis Biosciences → Massachusetts Technology Collaborative1 people: Orionis Biosciences → V-Bio Ventures1 people: Orionis Biosciences → Legend Biotech1 people: Orionis Biosciences → PJT Partners1 people: Orionis Biosciences → Results for Development1 people: Orionis Biosciences → Eurofins CDMO EuropeOrionis Biosciences67 peopleCAME FROMWENT TOGhent University10 peopleVIB7 peopleForma Therapeutics …6 peopleDana-Farber Cancer …3 peopleKU Leuven3 peopleVIB-UGent3 peopleMass General Brigham2 peopleMerck2 peopleargenx2 peopleKKata1 peopleMassachusetts Techn…1 peopleV-Bio Ventures1 peopleLegend Biotech1 peoplePJT Partners1 peopleResults for Develop…1 peopleEurofins CDMO Europe1 people
Data by CrustdataCrustdata

Most common previous employers of Orionis Biosciences staff: Ghent University (10), VIB (7), Forma Therapeutics (Now Novo Nordisk) (6), Dana-Farber Cancer Institute (3), KU Leuven (3), VIB-UGent (3). Former Orionis Biosciences employees most often moved to argenx (2), Kata (1), Massachusetts Technology Collaborative (1), V-Bio Ventures (1), Legend Biotech (1), PJT Partners (1).

Alumni worth knowing

Web traffic

orionisbio.com monthly visitors-1% month over month
1923,6457,0973,713202420252026
Data by CrustdataCrustdata

Traffic mix: 0% direct, 0% search, 0% social, 0% paid.

What this company is made of

Headcount by skillwhat people list on their profiles
BBiotechnology
26
MMolecular Biology
25
WWestern Blotting
23
BBiochemistry
22
LLife Sciences
20
CCell Culture
19
CCell Biology
18
PPolymerase Chain Reaction (PCR)
17
IImmunology
15
EELISA
15
Data by CrustdataCrustdata

Most common skills at Orionis Biosciences: Biotechnology (26), Molecular Biology (25), Western Blotting (23), Biochemistry (22), Life Sciences (20), Cell Culture (19), Cell Biology (18), Polymerase Chain Reaction (PCR) (17).

Where the team actually sits

Headcount by regionHQ: Waltham, Massachusetts, United States
FFlemish Region, Belgium
22
GGhent Metropolitan Area
13
GGreater Boston
7
MMassachusetts, United States
5
TTexas, United States
1
WWashington DC-Baltimore Area
1
NNew York, United States
1
BBruges Metropolitan Area
1
Data by CrustdataCrustdata

Orionis Biosciences people are concentrated in Flemish Region, Belgium (22), Ghent Metropolitan Area (13), Greater Boston (7), Massachusetts, United States (5).

Search footprint

Organic clicks
160
per month
Traffic worth
$1K
if bought as ads
Ranking keywords
277

Orionis Biosciences attracts about 160 organic search visits a month, traffic worth roughly $1K a month if bought through ads. It gained 24 ranking keywords and lost 26 in the last period.

Frequently asked

How many employees does Orionis Biosciences have?

Orionis Biosciences has 67 employees as of September 2026.

How much has Orionis Biosciences raised?

Orionis Biosciences has raised $79M in total, most recently a Series C round in October 2022.

Who founded Orionis Biosciences?

Orionis Biosciences was founded in 2015 by Nikolai Kley.

Who is the CEO of Orionis Biosciences?

Nikolai Kley (Founder, President and CEO) sits at the top of Orionis Biosciences's reporting structure, with 7 direct reports.

Where does Orionis Biosciences hire from?

The most common previous employers of current Orionis Biosciences staff are Ghent University (10 people), VIB (7 people), Forma Therapeutics (Now Novo Nordisk) (6 people).

Where do Orionis Biosciences employees go after leaving?

Former Orionis Biosciences employees most often move to argenx (2), Kata (1), Massachusetts Technology Collaborative (1).

How much traffic does Orionis Biosciences get from search?

Orionis Biosciences attracts about 160 organic search visits a month, worth roughly $1K a month in equivalent ad spend.

What skills do people at Orionis Biosciences have?

The most common skills among Orionis Biosciences staff are Biotechnology, Molecular Biology, Western Blotting, Biochemistry, Life Sciences.

Where is Orionis Biosciences's team located?

Orionis Biosciences staff are concentrated in Flemish Region, Belgium (22), Ghent Metropolitan Area (13), Greater Boston (7).

How big is Orionis Biosciences's research team?

Orionis Biosciences has about 43 people in Research, up 16% over the past year, as of September 2026.

How big is Orionis Biosciences's business development team?

Orionis Biosciences has about 8 people in Business Development, up 60% over the past year, as of September 2026.

Computed from 53 current and 22 former Orionis Biosciences profiles, as of September 2026. Source: Crustdata.

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