Spear Bio
Spear Bio is a biotech startup developing ultra-sensitive protein detection technology for disease diagnosis. The 53-person company raised $45M in Series A funding in July 2024 from investors including Bio-Techne and Foresite Capital.
The growth story
Spear Bio grew from 7 to 53 employees between 2022 and 2026, raising $45M along the way, most recently a Series A in July 2024.
About
Spear Bio sells protein biomarker detection technology that claims attomolar sensitivity from tiny sample volumes, targeting clinical researchers. Its SPEAR method uses a proprietary two-step amplification process to measure proteins at extremely low concentrations.
The company has grown to 53 employees since its 2021 founding, with recent Series A funding suggesting rapid expansion. Its backers include strategic investor Bio-Techne alongside venture firms like Foresite Capital and Maverick Ventures.
Founders and leadership
Research is the largest function with 20 employees, reflecting the company's technical focus. Leadership appears to combine scientific expertise with commercial backing from diagnostic industry investors.
The Spear Bio org chart
Feng Xuan (Co-Founder & CEO) leads 18 mapped leaders with 2 direct reports. Click +N to expand a team; names link to the person’s public profile.
Departments, and which ones grew
Headcount by function: Research 23 (+21% YoY), Business Development 9 (+13% YoY), Engineering 3 (-40% YoY), Human Resources 3 (0% YoY).
Talent flow
Nearly a quarter of profiled employees came from Quanterix, another ultrasensitive protein detection firm, suggesting targeted recruitment. Other common sources include Siemens Healthineers and Thermo Fisher Scientific, with some academic crossover from Tufts and Brigham and Women's Hospital.
Most common previous employers of Spear Bio staff: Quanterix (9), Siemens Healthineers (5), Bio-Techne (3), Tufts University (3), Thermo Fisher Scientific (3), Brigham and Women's Hospital (2). Former Spear Bio employees most often moved to SiPhox Health (2), Mansfield & Associates (1), Foresite Labs (1), BD (1), Diametryx (1), WuXi Biologics (1).
Alumni worth knowing
Web traffic
Traffic mix: 0% direct, 0% search, 0% social, 0% paid.
What this company is made of
Most common skills at Spear Bio: Polymerase Chain Reaction (PCR) (19), Cell Culture (19), Research Skills (18), Western Blotting (17), ELISA (17), Microsoft Office (17), Molecular Biology (16), Assay Development (14).
Where the team actually sits
Spear Bio people are concentrated in Massachusetts, United States (16), Greater Boston (14), United States (5), California, United States (3).
Search footprint
Spear Bio attracts about 42 organic search visits a month, traffic worth roughly $0K a month if bought through ads. It gained 28 ranking keywords and lost 28 in the last period.
What employees say
- Compensation
- 3.50 / 5
- Career opportunities
- 3.50 / 5
- Senior management
- 2.40 / 5
- Work-life balance
- 2.40 / 5
Frequently asked
Spear Bio has 53 employees as of September 2026.
Spear Bio has raised $45M in total, most recently a Series A round in July 2024.
Spear Bio was founded in 2021 by Peng Yin, Feng Xuan.
Feng Xuan (Co-Founder & CEO) sits at the top of Spear Bio's reporting structure, with 2 direct reports.
The most common previous employers of current Spear Bio staff are Quanterix (9 people), Siemens Healthineers (5 people), Bio-Techne (3 people).
Former Spear Bio employees most often move to SiPhox Health (2), Mansfield & Associates (1), Foresite Labs (1).
Spear Bio attracts about 42 organic search visits a month, worth roughly $0K a month in equivalent ad spend.
The most common skills among Spear Bio staff are Polymerase Chain Reaction (PCR), Cell Culture, Research Skills, Western Blotting, ELISA.
Spear Bio staff are concentrated in Massachusetts, United States (16), Greater Boston (14), United States (5).
Spear Bio has about 23 people in Research, up 21% over the past year, as of September 2026.
Spear Bio has about 9 people in Business Development, up 13% over the past year, as of September 2026.
Computed from 42 current and 33 former Spear Bio profiles, as of September 2026. Source: Crustdata.
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